HORIZON Reference Standards


Gene Editing

Understand disease mechanisms at the genomic level

Edit-R gene editing reagents

Optimized tools for high-confidence genome engineering.

Cell models

Work with relevant cell models, specific to any application. Ready-to-go or tailored to individual needs.

Gene Modulation Reagents

Understand disease  mechanisms at the genomic level

Gene knockdown

RNAi solutions by Dharmacon™ make gene silencing simple, so you can focus on the functional result!

Gene overexpression

CRISPR activation, cDNA & ORF reagents for reliable gene expression solutions to suit any workflow.

Top 3 tips for RNAi experiment success

Suggestions from our team of PhD trained scientists for getting your RNAi experiments working successfully!

Cell-based screening services

From target selection to patient stratification.
Working with you from consultation to delivery – providing functional genomic and cell panel screening services.

Functional genomic screens

Identify and characterize therapeutic targets and biomarkers

  • Determine relevant gene function
  • Investigate drug/gene interactions
  • Ensure data quality – generated using the latest CRISPR or RNAi reagents

Cell panel screens

Identify cells that respond to your therapeutic

  • Obtain trustworthy, reproducible data sets
  • Receive full analysis and comprehensive report
  • Screen in 2D and 3D models – spheroid and organoids

Screening libraries

Ensure library specificity – algorithm optimized guide RNA

  • Choose from CRISPR, CRISPRa and RNAi, pooled and arrayed formats
  • Freedom with custom library design

Immune cell-based assays

Evaluate therapeutic efficacy in immune-cell-based environments

Validation tools for molecular diagnostics

Consistency from assay development to routine monitoring

Next generation sequencing (NGS)

Bring consistency to NGS workflows

  • From assay development to routine monitoring
  • Mimic patient samples with commutable controls

Large panel NGS

Have confidence in large panel NGS worfklows

  • OncoSpan – the largest oncology reference standard
  • Multiple variant types, including structural and fusions

Sanger and qPCR

Reference standards at precise allele frequencies

  • single gene, multi-variant controls
  • well-characterized, commutable material

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